The Scalable Brain Atlas is financed by grants from these institutes/projects: It was first presented as a poster and demo session at the INCF booth of SFN 2009 in Chicago.Ī publication in Neuroinformatics followed in 2015. It uses exploratory work of Gleb Bezgin, creator of the CoCoMac-Paxinos3D tool. The Scalable Brain Atlas is developed by Rembrandt Bakker in collaboration with many others. The Multimodal atlas of gray short-tailed opossum brain by Chlodzinska, Majka et. The Marmoset atlas in Stereotactic Coordinates The Population based MRI/DTI atlas of the adult ferret ★ by Hutchinson et al. The Brodmann areas, projected on Conte69 space.
The BigBrain Nissl stained slices resampled at 400 µm. The LPBA40 parcellation, registered to SRI24 space. (2016), with maximum probability maps, anatomical and functional connectivity. The Brainnetome Atlas of Fan, Jiang et al. manually segmented brain, with cortical and subcortical parcellation. with maximum probability maps from Eickhoff et al. The JuBrain cytoarchitectonic atlas by Amunts, Zilles et al. The Harvard Oxford cortical parcellation, as distributed with FSL.
The Population-averaged DTI atlas of Veraart et al. The in vivo MRI template of Valdés-Hernández et al. The MR-histology atlas (age P80) of Calabrese et al. The Waxholm Space Sprague Dawley rat atlas of Papp et al. The INCF Waxholm Space for the mouse (2012). The Allen Mouse Brain Common Coordinate Framework version 3 (ABA_v3) ★.
TVB is also the choice of full-brain simulator in Europe’s digital research infrastructure EBRAINS and directly links to other large-scale neuroinformatics efforts such as the Allen Institute’s Mouse atlas or the Human Brain Project (HBP).Ī large, growing user base of clinicians and scientists are working every day with TVB, citing its scientific groundwork in well over 100 peer-reviewed publications.
TVB serves as the simulation engine in the world’s first clinical trial on predictive brain modeling in epilepsy surgery ( EPINOV). Today, TVB is a reference tool for full-brain simulation. Since its early beginnings as network equations scribbled on a bar coaster in 2008, TVB has gained wide recognition – demonstrated by regular invitations to participate at neuroinformatics events such as INCF conferences, and workshops dedicated to High Performance Computing (HPC) (such as organized by NSG).
You can simulate a human brain with TVB right now, for free and with access to the source code – on average MacBooks, faculty Linux servers or supercomputers like Piz Daint in CSCS Lugano. The key is TVB’s hybrid approach of merging individual anatomy from brain imaging data with state-of-the-art mathematical modeling. The Virtual Brain (TVB) takes a different approach and reduces complexity on the micro level to attain the macro organization: a TVB model of a patient's brain generates sufficiently accurate EEG, MEG, BOLD and SEEG signals by reducing the complexity millionfold through methods from statistical physics. While large-scale research initiatives simulate neurons and small brain regions at the cellular level on massively parallel hardware, they are still years away from clinical applications.
Simulating the human brain is the holy grail of neuroscience – offering a pioneering tool for understanding how our brain works and how to deal with its disorders like stroke, epilepsy or neurodegenerative diseases like Alzheimer’s or Parkinson’s.